Exons 2, 3, and 4, including the translation start site and short segments of flanking intronic sequence were replaced with a PGK-neo cassette. Correctly targeted ES cells were subsequently used to target Sftpd thus producing double mutant ES cells. (J:86022)
Basic Information
C57BL/6J x (Rb(11.16)2H x Rb(16.17)32Lub)F1
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count