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Exons 13, 14, and 15 were deleted by cre-mediated recombination of flanking loxP sites. The deleted region encoded the C-terminal transactivation domain that is involved in response to hypoxia, Cri2 recruitment, and efficient nuclear localization. Though a truncated protein consisting was detected, it was reported to be non-functional. (J:85763)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
