Exons 13, 14, and 15 were flanked by single loxP sites. The floxed region encodes the C-terminal transactivation domain that is involved in response to hypoxia, Cri2 recruitment, and efficient nuclear localization. (J:85763)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count