Sequence encoding cre recombinase was adjpoined to 9 kb of the rat tyrosine hydroxylase (Th) promoter. The rat Th promoter sequence drove expression of cre recombinase in catecholaminergic neurons. Expression was observed in the olfactory bulb, hypothalamic and midbrain dopaminergic neurons, the locus coeruleus, amacrime neurons of the retina, chromaffin cells of the adrenal medulla, and sympathetic ganglia. (J:85520)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x CBA)F2
--
Insertion
--
--
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12

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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