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2 kb of genomic sequence encompassing portions of exons 1 and 2 as well as the intervening intron were replaced with a cassette containing translational stop codons in all three reading frames, followed by a floxed neomycin resistance gene. The absence of protein was confirmed by Western blot analysis and by immunocytochemistry. (J:76322)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
