Sequence encompassing 2 kb of upstream sequence and exons 1 through 4 was replaced with a neo cassette inserted by homologous recombination. Northern blot analysis of testicualr RNA obtained homozygous mutant mice revealed an transcript containing neo but showed no endogenous message. (J:85175)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
Disruption caused by insertion of vector
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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