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The floxed neo cassette immediately downstrean of EGFP was excised from Serpinb6atm1Pib via cre mediated recombination in vitro. Expression of GFP recapitulated endogenous expression. Western blot analysis indicated an absence of normal protein in homozygous mutant spleen and thymus tissue. (J:85039)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
