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Sequence encompassing exons 5, 6, and 7 was replaced by PGK-neo inserted by homologous recombination. The deleted region encoded the enzymatically active extracellular portion of the mature protein that included apyrase-conserved regions 2 through 4. Although transcript 3' of the neo insertion was detected in homozygous mutant mice Northern blot analysis, apyrase activity and immunoreactivity were undetected. (J:76092)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
