Sequence encoding green fluorescent protein (GFP) was inserted into exon 2, replacing the first coding exon. A loxP site flanked neomycin resistance gene cassette that was included in the initial targeting vector was removed via cre-mediated recombination.The profile of GFP expression was consistent with that of the endogenous expression. (J:84836, J:106045)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
Insertion, Intragenic deletion
--
1
5
16

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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