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Exon 1 was replaced with a neomycin selection cassette inserted by homologous recombination. Protein was undetected by Western blot analysis of liver and intestinal extracts obtained from homozygous mutant mice. Absence of protein was further confirmed by immunohistochemical staining of the intestinal mucosa. (J:79282)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
