Log In|Sign Up
EN
Sequence encoding a 3' portion of human MLLT3 extending from nucleotide 1634 to the translation terminus replaced a 3' portion of murine Kmt2a exon 8. A downstream neo cassette was also included in the targeting vector for selection. The resultant fusion product putatively recapitulates the KMT2A(MLL)/MLLT3 protein produced in patients with the acute myeloid leukamia (AML) associated transloaction T(9;11)(p22;q23). (J:75959)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
