Bacterial Cre recombinase cDNA was subcloned between a 3 kb fragment of the mouse Col2a1 promoter and its chondrocyte-specific enhancer region. Transgenic founders were generated by pronuclear injection. Confirmation that Cre was expressed as expected was accomplished by crossing transgenic mice with mice carrying the Rosa26 reporter gene (J:84273)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6
--
Insertion
--
--
--
25

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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