A LacZ and a PGK-neomycin cassette were inserted just before the translation start site of the only gene exon. Chimeric mice were crossed with CAG-Cre mice to excise the neo cassette. Progeny of this cross were examined by PCR to check for mRNA expression. Expression was absent in tissues of homozygotes. (J:84414)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6NCrlj x CBA/JNCrlj)F1
Targeted
Insertion
--
1
2
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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