The floxed neo cassette was removed from intron 5 of Pdgfbtm3Cbet via in vivo cre mediated recombination. The stop codon that was inserted into exon 6 remained intact and precluded the translation of the retention motif. (J:84701)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count