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EN
An IRES-Cre cassette containing a neomycin selection gene flanked with frt sites was introduced into the 3' untranslated region downstream of the translational stop codon and upstream of the endogenous polyadenylation signal. Crossing with a flp deleter line to excise the neomycin resistance gene resulted in animals able to express Cre from the Hoxb1 locus without interfering with endogenous Hoxb1 activity. (J:84448)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
