The insertion of a gene trap cassette containing Beta-geo replaced ~36 kb of genomic sequence including exons 2 through 4. Transcript was undetected by Northern blot analysis of homozygous mutant mice using a probe corresponding to exon 18, common to all known splice variants. (J:84425)
Basic Information
Insertion of gene trap vector
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count