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A neomycin selection cassette replaced sequences from exons 4, 5, and 6. This results in the loss of kinase subdomains VII and VIII. Western blot analysis of protein extracts from E11.5 embryos indicated that both full length and truncated protein were absent. (J:84382)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
