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EN
A 7172 bp insert containing a splice acceptor, IRES, lacZ reporter gene and a neomycin resistance gene, all flanked by two FLP recombinase target sites was placed in intron 2 at the same time that loxP sites were inserted on either side of exon 3. Northern blot analysis established the absence of mRNA transcripts from the targeted gene and Western blots demonstrated the absence of protein products. (J:84096)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
