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A 486 bp fragment was replaced with a neomycin selection cassette inserted by homologous recombination. The deleted region corresponded to nucleotides 954 through 1440 of the cDNA and encoded the first zinc finger pairs. The insertion of the cassette was reported to disrupt the open reading frame at codon 99. Protein was undetected by Western blot analysis of homozygous mutant mice. (J:79652)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
