Exons 4 through 13, encoding the carboxyl portion of the PH domain and the entire SH2 domain, was replaced with a neomycin selection cassette. Northern blot analysis of homozygous mutant mice indicated an absence of transcript. (J:82584)
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Exons 4 through 13, encoding the carboxyl portion of the PH domain and the entire SH2 domain, was replaced with a neomycin selection cassette. Northern blot analysis of homozygous mutant mice indicated an absence of transcript. (J:82584)