The endogenous locus was disrupted by a polyadenylation signal inserted by homologous recombination. Neither transcript nor protein was detected by Northern and Western blot analyses of homozygous mutant splenic cells. Germline transmission of the allele generated in J:80920 was achieved in J:85014. (J:80920, J:84040)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count