Gene disruption was achieved by a modified gene-trapping strategy resulting in duplication of genomic sequence with a Beta-geo cassette inserted between the duplicates. Northern blot analysis proved that no gene product was present in homozygotes. (J:83818)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S6/SvEvTac
Gene trapped
Insertion of gene trap vector
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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