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The transgenic construct consists of a 170 kb fragment containing a modified Foxa3 locus in which exon 2 has been replaced with an IRES-cre cassette. Cre activity was first detected 8.5 dpc in the anterior intestinal portal, and later in the entire gut endoderm from stomach to colon. Efficient cre-mediated recombination was demonstrated in the stomach, liver, pancreas, and colon. (J:96332)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
