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EGFP-1 was inserted, beginning with its ATG start codon, "in frame" after the first 7 codons of the gene followed (in antisense orientation) by HPRT driven by the mouse PGK promotor. This insertion replaced the rest of the gene and 560 bp of the 3' untranslated region. Homozygous mutant mice failed to express target gene mRNA but did express EGFP mRNA. (J:83885)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
