Exon 2 of the gene, which contains the homeodomain, was replaced with an IRES-Beta geo cassette. X-gal staining of preimplantation embryos detected beta-geo in the inner cell mass of blastocysts and the central portion of the morula but not in 32-cell stage embryos or earlier. (J:83420)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S4/SvJae
Targeted
Insertion, Intragenic deletion
--
1
--
8

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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