As in Mafftm1Jeng, the entire coding region, except for the first 3 codons, was replaced with a cassette containing lacZ and a floxed selection region. Prior to implantation and germline transmission, the floxed region was excised via cre mediated recombination, leaving lacZ intact. (J:56405)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count