A gene trap vector consisting of LTR sites flanking a beta-geo cassette containing a splice acceptor and a PGK-btk cassette containing a splice donor integrated into an exon specific for the A isoform. Northern and Western blot analyses of brain and lung tissue indicated an absence of transcript and protein corrsponding to isoforms A and B. (J:83193)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S5/SvEvBrd
Gene trapped
Insertion of gene trap vector
--
1
--
20

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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