The floxed neo cassette was excised from Rtn4tm2Matl via in vivo cre mediated recombination in the germline. The disrupted exon encodes the first transmembrane domain of isoforms A, B, and C. (J:83192)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count