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The entire gene coding region was deleted and replaced with a Junb floxed PGK-neo knock-in cassette via homologous recombination. The floxed neo cassette was removed by transient expression of cre recombinase in correctly targeted ES cells. Northern blot analysis confirmed the expression pattern of the Junb knock-in sequence follows that of the endogenous gene. (J:75359)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
