The gene was disrupted by introducing an in-frame lacZ-neo fusion to exon 1 via homologous recombination. Absence of gene expression in homozygous mutant animals was confirmed by RT-PCR analysis of liver RNA. (J:46346)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count