Two coding exons were flanked with a floxed PGK-neo cassette and single loxP site via homologous recombination. The PGK-neo cassette was removed by transient expression of cre recombinase in correctly targeted ES cells. Resulting mutant animals carry loxP sites flanking 2 coding exons. (J:82911)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count