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A loxP site was inserted 3' of Hoxd11 and a Hoxd9/lacZ/loxP transgene ( Tg(Hoxd9/lacZ/neo)4Ddu) was inserted 26 kb upstream of the Hoxd13 start site via homologous recombination. Mutant animals were mated to cre deleter line Tg(CMV-cre)1Ipc to delete the entire region between the 2 loxP sites, which includes Evx2, Hoxd13, Hoxd12, and Hoxd11. (J:54543)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
