The gene was disrupted by replacement of exon 1 with a neomycin resistance cassette via homologous recombination. Absence of gene expression was confirmed by RT-PCR analysis of bone marrow macrophage RNA from homozygous mutant animals. (J:74478)
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The gene was disrupted by replacement of exon 1 with a neomycin resistance cassette via homologous recombination. Absence of gene expression was confirmed by RT-PCR analysis of bone marrow macrophage RNA from homozygous mutant animals. (J:74478)