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This allele is derived from Grin1tm1Slab by mating mutant animals to cre deleter strain TgN(CMV-cre)1Cgn, resulting in removal of the floxed neo cassette in intron 18 and allowing the asparagine to arginine subsitution at amino acid 598 (N598R) to be expressed. Western blot analysis showed that expression of the mutant allele is comparable to that of wild-type. (J:82670)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
