A 3.2 kb genomic fragment encompassing 3 exons was replaced with a floxed selection cassette that was subsequently removed in vitro via cre mediated excision. A single loxP site was left in place of exons 2, 2a, and 3, which encoded 158 residues of the T domain. (J:82458)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count