The N-terminal portion of the gene was deleted by replacement of exon 1 with a lacZ-PGK-neo cassette via homologous recombination. Absence of gene expression in homozygous mutant animals was confirmed by immunohistochemical analysis. (J:82459)
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The N-terminal portion of the gene was deleted by replacement of exon 1 with a lacZ-PGK-neo cassette via homologous recombination. Absence of gene expression in homozygous mutant animals was confirmed by immunohistochemical analysis. (J:82459)