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A 600 bp fragment encompassing exon 3 and surrounding intronic sequence was replaced with a neomycin selection cassette inserted by homologous recombination. The deleted region encoded extracellular loop E, which contains the conserved Asn-Pro-Ala motif and the merucury-sensitive cysteine at position 182. Neither transcript nor protein was by analyses of salivary glands obtained from homozygous mutant mice. (J:82588)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
