The gene was disrupted by insertion of a lacZ-neo cassette into a protein-coding exon via homologous recombination. Absence of gene expression was confirmed by Northern blot analysis of hypothalamus RNA. (J:57961, J:109294)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count