A lacZ-neomycin resistance cassette replaced most of exon 2, which contains the entire DNA binding domain, and placed lacZ under control of the endogenous promoter. RNase protection assays of livers from postnatal day 8 mice detected no difference in mRNA levels between homozygous mutant mice and wild-type mice. (J:53312)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
Insertion, Intragenic deletion
--
1
--
14

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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