This allele is derived from Nr1hrtm1Gstr. Exons 4 and 5 were deleted by mating Nr1h3tm1Gstr animals to cre deleter strain TgN(CMV-cre)1Cgn. Northern blot analysis of liver RNA from homozygous mutant animals detected a mutant transcript lacking 500 nucleotides corresponding to exons 4 and 5. (J:82096)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count