This allele is derived from Nr1hrtm1Gstr. Exons 4 and 5 were deleted by mating Nr1h3tm1Gstr animals to cre deleter strain TgN(CMV-cre)1Cgn. Northern blot analysis of liver RNA from homozygous mutant animals detected a mutant transcript lacking 500 nucleotides corresponding to exons 4 and 5. (J:82096)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
Intragenic deletion
--
1
1
48

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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