The 5' two-thirds of the endogenous coding region was replaced with a floxed neo cassette inserted by homologous recombination. The neo cassette was then excised via cre-mediated recombination. (J:66557)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count