A single loxP site was left in place of exons 6 and 7 after cre mediated recombination of loxP sites flanking loxP sites in the germline. Protein was undetected by Western blot analysis of MEFs and splenocytes obtained from homozygous mutant mice. (J:77233)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count