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Approximately 20 kb of endogenous sequence was replaced with an IRES-beta-geo cassette. The deleted sequence contained 7 exons encoding the cytokine receptor domains (amino acids 85 through 444). The expression pattern of the beta-galactosidase gene recapitulated that of the endogenous gene. (J:82048)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
