Cre-mediated excision of the floxed EGFP sequence from Egr2tm1Jchn enabled expression of sequence encoding the dipterhia toxin A subunit (DT) which had replaced the endogenous 5' coding region. Expression of DT putatively results in the elimination of boundary cap cells around E11.5. (J:82071)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S2/SvPas
Targeted
Insertion, Intragenic deletion
--
1
5
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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