A cDNA sequence encoding EGFP was inserted in place of the start codon in exon 2 of the endogenous locus. A single loxP site remained between the EGFP sequence and the coding region of exon 2. Expression of EGFP was detected in all hempatopoietic tissues of heterozygous mutant mice. The insertion did not disrupt the expression patterns of neighboring genes, Ly6i and Ly6e. (J:82052)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129X1/SvJ
Targeted
Insertion, Intragenic deletion
--
1
--
7

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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