A 5' loxP site was introduced into intron 2 and a 3' loxP site was introduced into intron 4 via homologous recombination. An frt-flanked neo cassette was also introduced into the 3' site for positive selection. (J:81795)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count