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A 5.7 kb genomic fragment encompassing exons 4 through 11 was replaced with a PGK-neo cassette inserted by homologous recombination. The deleted region corresponds with nt 445 through 1172 of the cDNA. Absence of the normal protein in homozygous mutant mice was indicated by flow cytometric analysis of spleen and peritoneal exudate cells. (J:71097)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
