A 196 kb BAC carrying the human LIPG genomic sequence was used for the transgene. Transgene expression in brain, aorta, heart, lung, kidney, and spleen was confirmed by RNase protection assay. Transgene mRNA expression and protein expression was determined to be 3.2-fold and 1.9-fold that of endogenous mouse mRNA and protein expression, respectively. (J:81821)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6
--
Insertion
--
1
--
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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