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The transgenic construct encodes a tamoxifen-inducible fusion protein consisting of cre recombinase and a mutated human estrogen receptor ligand-binding domain fused to the mouse Tek promoter and 10.5 kb of the first intron. Transgene expression in endothelial cells of the liver and kidney was confirmed by immunohistochemical analysis. (J:81649)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
