Cre-mediated excision of the floxed neo cassette from Csnk2btm1Bb left the promoter and exons 1 and 2 flanked by single loxP sites. Western blot analysis of ES cells harboring this allele indicated that the presence of the loxP sites did not interfere with protein expression. (J:81637)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count